Alan’s Sixth Provocative Discovery:
Almost by sheer luck Alan was able to obtain simultaneously five samples of a rare and fatal brain cancer called Glioblastoma Multiforme. Remember that the CDC through Livengood and Gilmore’s work had shown that Borrelia burgdorferi seeks out human glial cells in the brain.
So once again using his species-specific FISH stains, Alan tested cancers for the presence of Borrelia and it was clear that Borrelia was associated with the tumors. What role Borrelia played in the formation remains unclear, but one has to ponder the possibility that antibiotics might have delayed or even stopped the cancers from forming?
Subsequently nematode worms were found in Glioblastoma multiforme brain tumors.
Back in the early 90s Dr. Paul H. Duray had speculated that some cancer-like conditions seen in Lyme patients were probably due to Borrelia bacteria, but proving that connection eluded him. Paul often collected and froze tissues sent to him especially granulomas (sarcoidosis), lymphomas, and others. These samples and Paul’s research were all lost when he died unexpectedly.
What does this mean to Glioblastoma patients?
If a patient has Borreliosis we know they are at risk. So aggressive antibiotic treatment must be given. If the patient develops a Glioblastoma then antibiotics and an antiparasitic agent should be considered. If we find the mechanism by which Borrelia induces this cancer, we may have better answers to both diagnosis and treatment.